Antimicrobial Conjugated Oligoelectrolytes Containing Triphenylphosphonium Solubilizing Groups
نویسندگان
چکیده
Triphenylphosphonium functionalization of a conjugated oligoelectrolyte (COE) with stilbene core improved its spectrum activity to include ESKAPE pathogens and mycobacteria while crucially retaining the membrane-perturbing mode action characteristic COEs. The efficacy lead compound in vivo highlights potential COE molecular platform for designing more effective antibiotics. More information can be found Research Article by G. C. Bazan co-workers (DOI: 10.1002/chem.202203803).
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ژورنال
عنوان ژورنال: Chemistry: A European Journal
سال: 2023
ISSN: ['0947-6539', '1521-3765']
DOI: https://doi.org/10.1002/chem.202300862